Acute Hepatitis Panel
Acute Hepatitis Panel
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Acute Hepatitis Panel
Diagnose and Understand Recent Hepatitis Infections
The Acute Hepatitis Panel is a set of blood tests used to detect recent (acute) infections of the liver caused by hepatitis A, B, or C viruses. It helps identify the type, timing, and severity of liver infection and assists healthcare providers in choosing the most appropriate care.
🧪 What Does the Acute Hepatitis Panel Measure?
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Hepatitis A (HAV): Detects IgM antibodies, which appear early in an acute infection.
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Hepatitis B (HBV): Includes:
- HBsAg (Hepatitis B surface antigen): Indicates current infection
- HBcAb (Core antibody): Suggests exposure
- Anti-HBs (Surface antibody): Reflects immunity or recovery
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Hepatitis C (HCV): Checks for anti-HCV antibodies. If positive, further HCV RNA testing confirms active infection.
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The presence of IgM antibodies generally indicates a recent acute infection.
📌 Why Is This Test Performed?
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Diagnose acute hepatitis caused by HAV, HBV, or HCV
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Determine the cause of liver inflammation or jaundice
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Investigate symptoms such as abdominal pain, fatigue, dark urine, or yellowing skin
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Evaluate transmission risk to others in infectious cases
📊 How to Interpret Results
Result |
Meaning |
Positive IgM antibodies |
Acute infection likely present |
Positive HBsAg |
Active Hepatitis B infection |
Positive Anti-HCV |
Past or current Hepatitis C infection (confirm with RNA test) |
Negative results |
No recent infection detected |
Positive HBsAg + anti-HBc IgM |
Likely acute Hepatitis B infection |
⚠️ What Can Affect Results?
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Timing of testing – Antibodies may not appear immediately after exposure
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Recent vaccinations or past infections can cause positive antibody results
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Chronic liver disease may alter interpretation
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False positives may occur due to cross-reactivity
💉 How Is the Test Performed?
• A small blood sample is taken from a vein
• The sample is analyzed for antibodies and antigens associated with HAV, HBV, and HCV
🩺 When to See a Doctor
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Show symptoms of hepatitis (jaundice, fatigue, dark urine, etc.)
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Have had potential exposure to hepatitis
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Engage in high-risk behaviors (e.g., unprotected sex, sharing needles)
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Have abnormal liver enzyme results requiring further evaluation
✅ Key Takeaways
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The Acute Hepatitis Panel detects recent hepatitis A, B, or C infections