Acute Hepatitis Panel

Acute Hepatitis Panel

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Acute Hepatitis Panel 

Diagnose and Understand Recent Hepatitis Infections 

The Acute Hepatitis Panel is a set of blood tests used to detect recent (acute) infections of the liver caused by hepatitis A, B, or C viruses. It helps identify the type, timing, and severity of liver infection and assists healthcare providers in choosing the most appropriate care. 

🧪 What Does the Acute Hepatitis Panel Measure? 

  • Hepatitis A (HAV): Detects IgM antibodies, which appear early in an acute infection. 

  • Hepatitis B (HBV): Includes: 
      - HBsAg (Hepatitis B surface antigen): Indicates current infection 
      - HBcAb (Core antibody): Suggests exposure 
      - Anti-HBs (Surface antibody): Reflects immunity or recovery 

  • Hepatitis C (HCV): Checks for anti-HCV antibodies. If positive, further HCV RNA testing confirms active infection. 

  • The presence of IgM antibodies generally indicates a recent acute infection. 

📌 Why Is This Test Performed? 

  • Diagnose acute hepatitis caused by HAV, HBV, or HCV 

  • Determine the cause of liver inflammation or jaundice 

  • Investigate symptoms such as abdominal pain, fatigue, dark urine, or yellowing skin 

  • Evaluate transmission risk to others in infectious cases 

📊 How to Interpret Results 

Result 

Meaning 

Positive IgM antibodies 

Acute infection likely present 

Positive HBsAg 

Active Hepatitis B infection 

Positive Anti-HCV 

Past or current Hepatitis C infection (confirm with RNA test) 

Negative results 

No recent infection detected 

Positive HBsAg + anti-HBc IgM 

Likely acute Hepatitis B infection 

⚠️ What Can Affect Results? 

  • Timing of testing – Antibodies may not appear immediately after exposure 

  • Recent vaccinations or past infections can cause positive antibody results 

  • Chronic liver disease may alter interpretation 

  • False positives may occur due to cross-reactivity 

💉 How Is the Test Performed? 

• A small blood sample is taken from a vein 
• The sample is analyzed for antibodies and antigens associated with HAV, HBV, and HCV 

🩺 When to See a Doctor 

  • Show symptoms of hepatitis (jaundice, fatigue, dark urine, etc.) 

  • Have had potential exposure to hepatitis 

  • Engage in high-risk behaviors (e.g., unprotected sex, sharing needles) 

  • Have abnormal liver enzyme results requiring further evaluation 

✅ Key Takeaways 

  • The Acute Hepatitis Panel detects recent hepatitis A, B, or C infections 

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