Testosterone, Total

The Total Testosterone test measures the overall amount of testosterone in the blood, including both bound and free forms. Testosterone is the primary male sex hormone, but it is also important in females in smaller amounts. It plays a key role in sexual function, reproductive health, muscle mass, bone density, and overall well-being.

1. What Is Total Testosterone?

• Total testosterone includes both bound (to SHBG and albumin) and free testosterone.

• It provides a general overview of testosterone levels in the bloodstream.

• Most testosterone is bound to proteins and inactive, while only a small portion is free and active.

2. Why Is the Total Testosterone Test Performed?

This test is used to:

• Evaluate symptoms of low testosterone in men (e.g., fatigue, low libido, erectile dysfunction).

• Diagnose conditions like hypogonadism, infertility, or delayed puberty.

• Monitor testosterone replacement therapy.

• Assess androgen excess in women (e.g., hirsutism, acne, or irregular menstruation).

3. Total Testosterone Reference Range

• Men: 300 – 1,000 ng/dL (nanograms per deciliter)

• Women: 15 – 70 ng/dL

• Ranges may vary slightly between laboratories.

4. Interpreting Total Testosterone Results

🔹 Low Testosterone:

• In men: May suggest hypogonadism, pituitary dysfunction, or chronic illness.

• Can cause reduced libido, fatigue, depression, and muscle loss.

🔹 High Testosterone:

• In men: May result from testosterone supplementation, tumors, or anabolic steroid use.

• In women: Often linked to PCOS, adrenal disorders, or androgen-secreting tumors.

5. What Can Affect Testosterone Levels?

• Age (levels naturally decline with age)

• Time of day (highest in the morning)

• Stress, obesity, liver or kidney disease

• Medications (e.g., steroids, opioids, hormone therapies)

6. How Is the Test Performed?

• A blood sample is drawn, ideally between 7:00 AM and 10:00 AM.

• Fasting is typically not required unless specified by your provider.

7. When to See a Doctor

🚨 Contact your healthcare provider if you:

• Experience symptoms like low sex drive, erectile dysfunction, fatigue, or mood changes.

• Are concerned about hormone levels, fertility, or athletic performance.

• Are on or considering testosterone therapy and need evaluation or monitoring.

🔹 Key Takeaways

✅ Total testosterone provides an overall view of your body’s testosterone levels.

✅ Abnormal results may indicate hormonal imbalances that impact reproductive, metabolic, and emotional health.

✅ Proper interpretation often requires additional tests like Free Testosterone and SHBG.