Amylase

Amylase

The Amylase test measures the level of amylase enzyme in the blood or urine. Amylase is produced mainly by the pancreas and salivary glands, and it plays a key role in digesting carbohydrates. Elevated or decreased levels can indicate pancreatic disorders or other medical conditions.

1. What Is Amylase?

• Amylase is an enzyme responsible for breaking down starches into sugars during digestion.

• It is produced primarily in the pancreas and salivary glands.

• Abnormal levels may indicate issues with the pancreas, such as pancreatitis or a blockage.

2. Why Is the Amylase Test Performed?

The test is used to:

• Diagnose or monitor acute or chronic pancreatitis.

• Detect pancreatic duct obstructions or pancreatic cancer.

• Investigate abdominal pain or other digestive symptoms.

• Evaluate salivary gland disorders (e.g., mumps).

3. Amylase Reference Ranges

• Normal range (blood): 30 – 110 U/L (units per liter)

• Normal range (urine): 2 – 34 U/hour

• Reference ranges may vary depending on the laboratory and testing method.

4. How to Interpret Amylase Results

🔹 Elevated Amylase:

• Common in acute pancreatitis, usually rising within hours and returning to normal in a few days.

• May also be seen in pancreatic cancer, gallstones, gastrointestinal perforation, or mumps.

🔹 Decreased Amylase:

• May occur in chronic pancreatitis or severe pancreatic damage where enzyme production is impaired.

• Can also be seen in liver disease or cystic fibrosis.

5. What Can Affect Amylase Levels?

• Medications (e.g., diuretics, birth control pills, opiates)

• Alcohol consumption

• High triglycerides

• Recent abdominal surgery or trauma

6. How Is the Test Performed?

• Blood sample: Collected from a vein, usually no fasting required.

• Urine sample: Often collected over 24 hours to assess amylase clearance.

7. When to See a Doctor

🚨 Contact your healthcare provider if you experience:

• Sudden, severe abdominal pain

• Nausea and vomiting

• Fever or rapid pulse (possible signs of pancreatitis)

• Unexplained elevations in amylase levels

🔹 Key Takeaways

✅ Amylase is an enzyme that helps digest carbohydrates, produced mainly by the pancreas and salivary glands.

✅ Elevated amylase levels may suggest acute pancreatitis or other abdominal conditions.

✅ Low levels can occur with chronic pancreatic disease or liver disorders.